Concerns are being raised after four animals - three skunks and a horse - tested positive for rabies in southeast Missouri.
Aall four cases have been confirmed since the start of the year.
Rabies cases are rare in the cold-weather months. The four cases this year equaled the January-February total in Missouri for the previous five years.
The rabid skunks were in Douglas, Howell and Ste. Genevieve counties. Most recently, an American Quarter Horse from near Williamsville in Wayne County was first thought to have a muscle disease. After it died, it tested positive for rabies.